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DoseRite™ – Dosing and application for the anal canal

DoseRite was designed by two surgeons who recognized the value of prescription topical treatments but were unhappy with the imprecision of dosing and focus that often attended random compounding in tubes or jars and dependence upon digital or perianal application. Since each of these medications is "dose-dependent", precise dosing was an important issue in development of the device. Increasing efficacy, minimising side effects, and increasing patient compliance are the intended benefits.

DoseRite’s patented anal applicator provides a simple and painless way for patients to accurately apply fissure medication within the anal canal. The applicator’s side slotted design ensures medication is applied directly to the anoderm for efficient absorption by the internal sphincter muscle. A safety flange ensures the tip is inserted to a safe depth and the closed-end design prevents unwanted delivery in the rectum. DoseRite's proprietary adapter allows patients to transfer and apply a single dose of medication from a tube or jar without direct contact with the medication. As a result, side effects such are headaches are greatly reduced even at larger doses (0.3cc-0.5cc).¹

Eliminate Anal Fissure Pain with DoseRite

The key to anal fissure pain relief is maintaining a relaxed internal anal sphincter muscle. This will stop the vicious anal fissure cycle, resulting in reduced pain, more comfortable bowel movements, and improved blood flow to the area, which promotes healing.

Keep the internal sphincter muscle relaxed by applying topical medications such as Diltiazem, Nifedipine or Nitroglycerine to the tissue surrounding the anal sphincter muscle (anoderm) in the anal canal.¹ Studies show that applying these medications in the anal canal is more effective at relaxing the internal sphincter muscle than application around the outside of the anus.² Delivery into the rectum should also be avoided for effective relief.

Read more about the benefit of using DoseRite in these publications, Diseases of the Colon and Rectum and Nature.

Targeted Delivery of Medication

DoseRite’s patented applicator provides a painless and straightforward way for patients to apply medication inside the anal canal. The applicator’s side-slotted design ensures medication is applied directly to the anal mucosa (anoderm) in the anal canal for maximum absorption by the internal sphincter muscle. Using DoseRite three times per day provides prolonged relaxation of the anal sphincter muscle and significant pain relief.²

Simple, Accurate Medication Dosing

DoseRite also includes a seamless dosing method that includes a universal adaptor and dosing syringes that connect directly to the patient’s medication container. This seamless system allows patients to apply an accurate single dose every time for more consistent results and less wasted medication.

Conveniently Packaged for Patients

Take the guesswork out of anal fissure treatment with DoseRite's Anal Fissure Kit.

Additional Videos

DoseRite Jar Demonstration

DoseRite includes a seamless dosing method that uses a universal adaptor and dosing syringes that connect directly to a patient's medication container. This clever system allows patients to apply an accurate single dose every time for more consistent results and less wasted medication.

DoseRite Medication Tube Demonstration

DoseRite helps patients get the relief they need by taking the guesswork out of anal fissure treatment. Watch the following video to see how DoseRite makes dosing from your medication tube simple and accurate.

 

Additional product information and resources are available at www.doserite.info

1. Stewart, D. et al, Clinical Practice Guidelines for the Management of Anal Fissures. Diseases of the Colon & Rectum Volume 60: 1 (2017) 9. DOI: 10.1097/DCR.0000000000000735

2. Torrabadella L., Salgado G., Controlled Dose Delivery in Topical Treatment of Anal Fissure: Pilot Study of a New Paradigm. Dis Colon Rectum 2005; 49: 865–868. DOI: 10.1007/s10350-005-0270-y
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Resources

DoseRite data sheet

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Patient information guide and instructions for use

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Controlled dose delivery in topical treatment of anal fissure: pilot study of a new paradigm

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Frequently asked questions

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